The spike is largely due to an outbreak at the Cedar Meats Australia abattoir in Melbourne: 11 of the new cases are linked to the facility, which already had 34 confirmed cases.
Another one of the new cases is in mandatory hotel quarantine, two came through drive-through testing clinics and three of the cases are under investigation, Victorian Treasurer Tim Pallas said this morning.
Eleven people are being treated in Victorian hospitals, including six patients in intensive care.
A total of 152,000 tests have been undertaken.
The treasurer said 421 cases have been acquired through community transmission.
