Four or five people are unaccounted for, officials added.
The bus burst into flames after falling around 10 metres from the overpass.
Prime Minister Giorgia Meloni expressed her “most profound condolences” and said she was thinking of the victims and their families and friends.
Police sources said that two children were among the victims and Veneto Governor Luca Zaia confirmed that minors were involved in the disaster.
“The victims and injured are of various nationalities, not just Italians,” Zaia said in a social-media post.
“The operation to extract the bodies (from the wreckage) and identify them is ongoing.”
ANSA