Coach Gennaro Gattuso has called up Bologna winger Nicolò Cambiaghi to take his place.
If Italy beat Northern Ireland, they will face the winner of the other semifinal between Wales and Bosnia and Herzegovina on March 31 away from home.
If they lose, they will have to play a friendly against the other defeated semi-finalist.
Italy have missed the last two World Cups after failing to qualify directly from the group stage and being ejected in the subsequent playoffs.
ANSA