Draghi and his wife, Maria Serenella Cappello, were vaccinated at a pop-up centre at Rome’s central Termini station, a government spokesperson said.
Draghi and Cappello, both 73, were eligible for vaccination by age group in the Lazio region surrounding Rome, which extended the campaign to people in their 70s earlier this month and is now vaccinating people in their late 60s and older.
Italy halted the use of the AstraZeneca vaccine for several days earlier this month following fears of a link to blot clots.
It resumed using the vaccine several days later, after the European Medicines Agency (EMA) gave the all-clear.
The World Health Organization (WHO) has also confirmed the AstraZeneca vaccine is safe to use.
Draghi, who took office last month, has promised to ramp up the number of vaccinations in Italy, which was the first European country to face the full force of the pandemic and is currently battling a third wave of infections.
Another 3 million doses are due to be delivered to Italy “by the end of the month”, according to COVID-19 emergency commissioner Francesco Paolo Figliuolo, while the single-shot Johnson & Johnson vaccine is expected to arrive from April 19.
