It comes as Italy recorded 10,874 new cases of coronavirus in the past 24 hours, up from 9338 on Monday.
The two regions – at opposite ends of the country – have been hit hardest by the nation’s second wave of infections.
Lombardy, in the north, suffered a brutal first wave of the pandemic and accounts for more than 17,000 of Italy’s 36,705 deaths.
Campania successfully dodged the first wave of infections and declared itself COVID-free in June, but cases started to rise again in August and the southern region is not far behind Lombardy now.
Any measures imposed at a local level need to be coordinated with the central government.
Campania’s regional governor announced on Tuesday afternoon that the region had requested a curfew from 11:00 pm on Friday, Italian media reported.
“Everything will close at 23:00 on Friday in Campania, the same as Lombardy has requested,” Campania governor Vincenzo De Luca said.
He said Campania would ask for the all-clear from central government “by the end of the day” and that “all activities and transport will be halted from this weekend on”.
He gave no details immediately on how it would work or how long it would last.
De Luca closed schools last week, less than a month after they reopened, and recently banned medics from speaking to the press unless they had permission from the regional administration.
In Lombardy, the curfew from 11:00 pm to 5:00 am is expected to begin on Thursday night and last until at least November 13.
Health Minister Roberto Speranza approved the measure on Monday, after an hours-long meeting.
“It’s an appropriate and symbolically important initiative that shouldn’t have particularly serious economic consequences,” Regional President Attilio Fontana told Italian daily La Repubblica on Tuesday.
Lombardy’s curfew is expected to only allow people to leave their home for reasons of health, work or necessity.
Under the new decree, most medium and large shopping centres are expected to be ordered to close at weekends, although there will be exceptions for shops selling food.
On Saturday, Lombardy ordered its bars to shut at midnight and prohibited the consumption of food and drink in public outside areas.
Italy’s government has over the past two weeks repeatedly tightened national restrictions to try to stem the new wave of infections.
Rules include banning amateur contact sports and school trips, and restricting bars and restaurants to table service after 6:00 pm.
However Lombardy is the first part of the country to impose a curfew.
Prime Minister Giuseppe Conte has repeatedly said he does not envision another nationwide lockdown, which would further sap Italy’s struggling economy, but has said that he would not rule out localised restrictions.
