The man died at Toowoomba hospital, west of Brisbane.
The state reported 57 new cases overnight, taking the total to 835.
Hundreds of people are still trying to get into Queensland despite the state shutting down its border with NSW.
Premier Annastacia Palaszczuk is ramping up the border crackdown as people continue to ignore the ban on non-essential travel.
From Friday, anyone who does not have a state government permit proving they have a legitimate reason for cross-border travel will be denied entry into Queensland.
On a positive note, the Premier announced around 2000 Queenslanders have so far pledged to join the state’s Care Army to help elderly and vulnerable during the crisis.