The 62-year-old woman, who is from Adelaide, died in the Royal Adelaide Hospital overnight after contracting coronavirus on the Ruby Princess cruise ship.
The woman is among 85 cases in the state linked to the doomed cruise ship, which is now the subject of a police criminal investigation.
The Ruby Princess is now berthed in Wollongong as NSW homicide detectives piece together how ill passengers were allowed to leave ship.
The ship is responsible for more than 600 of Australia’s coronavirus cases and at least 11 deaths.
South Australia’s latest death is the second in two days after grandfather Francesco “Frank” Ferraro died on Monday night.
Ferraro, 75, of Campbelltown, contracted the virus after attending a family wedding in Melbourne last month.
Authorities yesterday confirmed four more cases of the virus had emerged in South Australia, bringing the total number of infections to 415.
