Those to be probed in the first of a series of investigations include the president of the province of Pescara, Antonio Di Marco, Farindola Mayor Ilario Lacchetta and the hotel's manager, Bruno Di Tommaso.
Also being questioned are two provincial officials, Paolo D'Incecco and Mauro Di Blasio, and Farindola municipal worker Enrico Colangeli.
A prosecutor said the six were being probed for "negligence, imprudence and recklessness", after being accused of not foreseeing the danger of an avalanche, and not preventing or managing the risks.
Prosecutors affirmed they would also be looking into local authorities' past plans for dealing with extreme weather, heavy snowfall and avalanches.
Lawyers for relatives of the victims said other possible suspects would be announced later.